GENERAL CATALOGUE
YZ129
HY-114413 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-114413
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Catalog No: HY-114413
CAS No: 1643120-60-8
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 HSP90 with an IC50 of 820 nM on NFAT nuclear translocation. YZ129-induced GBM cell-cycle arrest at the G2/M phase promotes apoptosis and inhibited tumor cell proliferation and migration.
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