XRCC4 Mouse Monoclonal Antibody

Description

EnkiLife offers the XRCC4 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,IHC,ICC,IP application. Alternative Names of Immunogen: X ray repair cross complementing protein 4; DNA repair protein XRCC4; DNA double strand break repair. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200,IP 1:10-1:20 Background: Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.