GENERAL CATALOGUE
W1131 TFA
HY-153190A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-153190A
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Manufacturer product page
medchemexpress.com/w1131-tfa.htmlCatalog No: HY-153190A
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
W1131 TFA is a potent STAT3 inhibitor that induces ferroptosis. W1131 inhibits cancer progression in subcutaneous xenograft, organoid, and PDX models of gastric cancer. W1131 effectively alleviates cancer cell chemoresistance to 5-FU HY-90006 . W1131 regulates the cell cycle, DNA damage response, and oxidative phosphorylation, including the IL6-JAK-STAT3 pathway and the ferroptosis pathway.
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