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VU0155041, positive allosteric mGluR4 agonist
ab120244 · 10 mg
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Catalog No: ab120244
Category: Biochemicals
Pack Size: 10 mg
Brand: abcam
Description
MW 316.2 Da, Purity >99 %. Positive allosteric selective modulator at mGluR4 EC50 values are 798 and 693 nM at human and rat mGluR4 receptors, respectively . It has advantages over PHCCC ab120043 as it is more potent. Shows limited blood-brain barrier permeability. Active in behavioural models of Parkinsons disease following icv injection. Available in water-soluble form - please see VU0155041 sodium salt ab120248 .
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