GENERAL CATALOGUE
Voruciclib
HY-12422 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-12422
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Catalog No: HY-12422
CAS No: 1000023-04-0
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Voruciclib is an orally active and selective CDK inhibitor with Ki values of 0.626 nM-9.1 nM. Voruciclib potently blocks CDK9, the transcriptional regulator of MCL-1. Voruciclib represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma DLBCL .