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VH298, VHL inhibitor
ab230370 · 1 mg
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Catalog No: ab230370
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam
Description
MW 523.6 Da, Purity >98 %. VH298 is a cell permeable compound that binds tightly to VHL KD = 80- 90 nM in in vitro binding assays leading to cellular accumulation of HIF1-alpha. VH298 selectively stabilizes hydroxylated HIF1-alpha and induces HIF-dependent transcription.