GENERAL CATALOGUE
Verrucarin A
HY-107426 · 1 mg
MedChemExpress · Cat: HY-107426
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medchemexpress.com/verrucarin-a.htmlCatalog No: HY-107426
CAS No: 455863
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
Verrucarin A Muconomycin A , a Type D macrocyclic mycotoxin derived from the pathogen fungus Myrothecium verrucaria, is an inhibitor of protein synthesis. Verrucarin A inhibits growth of leukemia cell lines and activates caspases and apoptosis and inflammatory signaling in macrophages. Verrucarin A effectively increased the phosphorylation of p38 MAPK and diminished the phosphorylation of ERK/Akt. Verrucarin A caused cell cycle deregulation through the induction of p21 and p53.
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