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UBP310, GluK1 and GluK3 selective antagonist
ab120168 · 10 mg
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Catalog No: ab120168
Category: Biochemicals
Pack Size: 10 mg
Brand: abcam
Description
MW 353.35 Da, Purity >98 %. GluK1 formerly GluR5 and GluK3 formerly GluR7 receptor selective antagonist Kb =10 nM and IC50 = 23 nM, respectively . IC50 values are >100 muM at recombinant human GLUA2 formerly GluR2 , GluK2 formerly GluR6, GluK2/GluK5 formerly GluR6/KA2 and GluK2/GluK3 formerly GluR6/GluR7 . Selective over native AMPA receptors Kd = 83 muM and exhibits no activity at NMDA and Group I mGlu receptors at concentrations of up to 10 muM.
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