GENERAL CATALOGUE
Tubulin/HDAC-IN-3
HY-149578 · 50 mg
MedChemExpress · Cat: HY-149578
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medchemexpress.com/tubulin-hdac-in-3.html
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Catalog No: HY-149578
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
Tubulin/HDAC-IN-3 compound 12a is a potent tubulin/HDAC dual inhibitor. Tubulin/HDAC-IN-3 effectively disrupts tubulin polymerization IC50: 5.4 ?M . Tubulin/HDAC-IN-3 exhibits potent HDAC1/8 inhibitory activities, with IC50 values of 0.155 and 0.177 ?M, respectively. Tubulin/HDAC-IN-3 works through blocking cellular cycle, inducing apoptosis and inhibiting colony formation.