TTK21

Description

TTK21 is an activator of the histone acetyltransferases CBP/p300. TTK21 passes the bloodAAasAasAabrain barrier, induces no toxicity, and reaches different parts of the brain when conjugated to glucose-based carbon nanosphere CSP . TTK21 has beneficial implications for the brain functions of neurogenesis and long-term memory.CSP-TTK21 can ameliorate A?-impaired long-term potentiation LTP . CSP-TTK21 may enhance the transcription of genes that promote synaptic health and cognitive function. CSP-TTK21 is orally effective and leads to improvements in motor functions, histone acetylation dynamics in a spinal injury rat model.