

HY-50936S · 1 mg
MedChemExpress · Cat: HY-50936S
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medchemexpress.com/trabectedin-d3.htmlDescription
Trabectedin D3 Ecteinascidin 743 D3 is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has tje potential for soft tissue sarcoma and ovarian cancer treatment.