GENERAL CATALOGUE
Totrombopag choline
HY-135041 · 50 mg
MedChemExpress · Cat: HY-135041
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medchemexpress.com/totrombopag-choline.htmlCatalog No: HY-135041
CAS No: 851606-62-7
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
Totrombopag SB-559448 choline is an orally effective thrombopoietin receptor TpoR agonist. By activating TpoR, Totrombopag choline initiates an intracellular signaling cascade mediated by JAK2 kinase and the transcription factor Stat5, a signaling process that is the primary mechanism regulating megakaryocyte growth and differentiation into platelets. Totrombopag choline can be used to study platelet production and megakaryocyte biology.