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Thalidomide-propargyl
GENERAL CATALOGUE

Thalidomide-propargyl

HY-126457 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-126457

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Catalog No: HY-126457
CAS No: 2098487-39-7
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

Thalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-propargyl can be connected to the ligand for protein by a linker to form the IMiD containing PROTACs. Thalidomide-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition CuAAc with molecules containing Azide groups.

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