GENERAL CATALOGUE
Tauroursodeoxycholate dihydrate
HY-19696B · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-19696B
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Catalog No: HY-19696B
CAS No: 117609-50-4
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Tauroursodeoxycholate dehydrate is an orally active taurine conjugate of Ursodeoxycholic acid HY-13771 . Tauroursodeoxycholate dehydrate inhibits caspase-3/7, Apoptosis, IRE1?/TRAF2/NF-?B, prevents JNK phosphorylation, inhibits ROS generation, and activates Akt signaling. Tauroursodeoxycholate dehydrate prevents cataract formation, reduces renal tubular damage in type 2 diabetic mice, reduces I/R injury in liver, and inhibits intestinal inflammation and barrier disruption in nonalcoholic fatty liver disease.
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