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SR1001, RORalpha and RORgammat inverse agonist
ab141462 · 5 mg
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Catalog No: ab141462
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 477.4 Da, Purity >98 %. Potent, selective RORalpha and RORgammat inverse agonist Ki values are 172 and 111 nM for RORalpha and RORgamma respectively . Suppresses IL-17 promoter driven transcriptional activity. Inhibits TRAP220 nuclear receptor box 2 peptide interaction IC50 = 117 nM . Shows immunosuppressant effects in vivo..
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