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Spiperone hydrochloride, 5-HT and D2-like receptor antagonist
ab120549 · 50 mg
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Catalog No: ab120549
Category: Biochemicals
Pack Size: 50 mg
Brand: abcam
Description
MW 431.9 Da, Purity >98 %. 5-HT and D2-like receptor antagonist. IC50 values are 1.6 and 15 nM at 5-HT2 and 5-HT1C receptors, respectively. Ki values are 0.06 D2 , 0.6 D3 , 0.08 D4 , 350 D1 and 3500 nM D5 . Potently enhances intracellular Ca2+ levels. Additionally activates Ca2+-activated Cl- channels CaCC to induce Cl- secretion.
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