GENERAL CATALOGUE
Smilagenin
HY-106353 · 10 mM * 1 mL in Ethanol
MedChemExpress · Cat: HY-106353
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medchemexpress.com/smilagenin.htmlCatalog No: HY-106353
CAS No: 126-18-1
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in Ethanol
Brand: MedChemExpress
Description
Smilagenin SMI is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases. Smilagenin SMI improves memory of aged rats by increasing the muscarinic receptor subtype 1 M1 -receptor density. Smilagenin SMI attenuates A? 25-35 -induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD.