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SMI-4a, ATP-competitive Pim kinase inhibitor
ab141367 · 5 mg
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Catalog No: ab141367
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 273.23 Da. Potent, selective, cell-permeable, ATP-competitive Pim-1 kinase inhibitor IC50 = 17 nM . Moderately potent against Pim-2 kinase. Selective versus a panel of other serine/threonine and tyrosine kinases. Inhibits the growth of myeloid and lymphoid cell lines. Induces cell cycle arrest in leukemia and prostate cancer cells.
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