GENERAL CATALOGUE
SIAIS164018 hydrochloride
HY-147219A · 1 mg
MedChemExpress · Cat: HY-147219A
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medchemexpress.com/siais164018-hydrochloride.htmlCatalog No: HY-147219A
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
SIAIS164018 hydrochloride is a PROTAC-based ALK and EGFR degrader, with IC50 value of 2.5 nM and 6.6 nM for ALK and ALK G1202R, respectively. SIAIS164018 hydrochloride strongly inhibits cancer cells migration and invasion, causes G1 cell cycle arrest and induces apoptosis. SIAIS164018 hydrochloride exhibits better property than Brigatinib HY-12857 .
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