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S1RA
GENERAL CATALOGUE

S1RA

HY-18099 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-18099

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medchemexpress.com/s1ra.html
Catalog No: HY-18099
CAS No: 878141-96-9
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

S1RA E-52862 is a highly selective ?1 receptor ?1R antagonist with Kis of 17 nM and 23.5 nM for human ?1R and guinea pig ?1R, respectively. S1RA has Moderate antagonistic activity for human 5-HT2B receptor Ki= 328 nM . S1RA has antinociceptive effects in neuropathic pain models. S1RA prevents mechanical and cold hypersensitivity in Oxaliplatin HY-17371 -treated mice.

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