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Ro 25-6981 maleate salt (mM/ml), NR2B antagonist
ab146695 · 20 mM/mL
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Catalog No: ab146695
Category: Biochemicals
Pack Size: 20 mM/mL
Brand: abcam
Description
MW 455.5 Da, Purity >98 %. Potent, highly selective, activity-dependent blocker of NMDA receptors that contain the NR2B subunit IC50 values are 0.009 and 52 muM at NR1C/NR2B and NR1C/NR2A, respectively . Displays no significant activity at kainate/AMPA receptors, Na+ and Ca2+ channels at concentrations showing maximal protection in neurotoxicity tests. Neuroprotective actions in vivo and in vitro.
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