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Ribociclib (LEE011)
ab285415 · 5 mg
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Catalog No: ab285415
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 434.5 Da, Purity >98 %. Ribociclib is a potent cyclin-dependent kinase CDK inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. LEE011 has been shown to reduce proliferation in 12 of 17 human neuroblastoma-derived cell lines by inducing cytostasis mean IC50 = 306 nM in sensitive lines .
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