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RG 108, non-nucleoside DNA methyltransferase inhibitor (DNMT)
ab141013 · 5 mg
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Catalog No: ab141013
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 334.3 Da, Purity >99 %. Novel, non-nucleoside DNA methyltransferase DNMT inhibitor, capable of interacting with the DNMT1 active site IC50 = 115 nM . Inhibits DNA methylation in human cancer cell lines. Reactivates several epigenetically silenced tumour suppressor genes in vitro. Capable of enhancing the efficiency of induced pluripotent stem cell iPS generation.
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