Recombinant Mouse GHR (C-Fc)

Description

EnkiLife provides the Recombinant Mouse GHR (C-Fc) protein,aslo know as growth hormone binding protein,growth hormone receptor,serum binding protein,Somatotropin receptor;GHR,GH receptor,GHBP, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse Growth Hormone Receptor is produced by our Mammalian expression system and the target gene encoding Met1-Gln273 is expressed with a human IgG1 Fc tag at the C-terminus.Accession:Q3UP14. Expression Host:Human Cells.Species:Mouse.Predicted Molecular Mass:58.3 KDa. Background:Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.