Recombinant Mouse CXCL2

Description

EnkiLife provides the Recombinant Mouse CXCL2 protein,aslo know as MIP-2,chemokine ligand 2,C-X-C motif chemokine 2,GRO beta,GRO2,GROB,Gro-beta,Growth-regulated protein beta,Macrophage Inflammatory Protein-2-alpha,melanoma growth stimulatory activity beta,cxcl2,MGSA-b,MGSA-beta,MIP2A,MIP2-alpha,SCYB2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse C-X-C Motif Chemokine 2 is produced by our E.coli expression system and the target gene encoding Ala28-Asn100 is expressed.Accession:P10889. Expression Host:E.coli.Species:Mouse.Predicted Molecular Mass:7.9 KDa. Background:C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.