Recombinant Mouse CCL9

Description

EnkiLife provides the Recombinant Mouse CCL9 protein,aslo know as C-C motif chemokine 9,CCF18,Macrophage inflammatory protein 1-gamma,Macrophage inflammatory protein-related protein 2,Small-inducible cytokine A9,Scya10,Scya9 and CCL9, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Mouse C-C Motif Chemokine 9 is produced by our E.coli expression system and the target gene encoding Gln22-Gln122 is expressed.Accession:P51670. Expression Host:E.coli.Species:Mouse.Predicted Molecular Mass:11.6 KDa. Background:C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. Monokine has inflammatory, pyrogenic and chemokinetic properties. It circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor，it activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors. CCL9 can activate osteoclasts through its receptor CCR1 (the most abundant chemokine receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption.