Recombinant Human Isomerase2 (N-6His)

Description

EnkiLife provides the Recombinant Human Isomerase2 (N-6His) protein,aslo know as Isopentenyl-Diphosphate Delta-Isomerase 2,Isopentenyl Pyrophosphate Isomerase 2,IPP Isomerase 2,IPPI2,IDI2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Isopentenyl Pyrophosphate Isomerase 2 is produced by our E.coli expression system and the target gene encoding Met1-Val227 is expressed with a 6His tag at the N-terminus.Accession:Q9BXS1. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:28.9 KDa. Background:Isopentenyl Pyrophosphate Isomerase 2 (IDI2) belongs to the IPP isomerase type 1 family. Both isozymes, IDI1 and IDI2 are localized to the peroxisome by a PTS1-dependent pathway. IDI2 is expressed in skeletal muscle, which contains one nudix hydrolase domain. IDI2 binds one magnesium per subunit. IDI2 catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). It is reported that IDI2 is regulated independently from IDI1, by a mechanism that may involve PPAR-α.