GENERAL CATALOGUE
(Rac)-BDA-366
HY-101083A · 50 mg
MedChemExpress · Cat: HY-101083A
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Catalog No: HY-101083A
CAS No: 142645-19-0
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Rac -BDA-366 example 2 is the despinner of BDA-366 HY-101083 . BDA-366 is a potent Bcl-2 antagonist Ki=3.3 nM , binding Bcl-2-BH4 domain with high affinity and selectivity. BDA-366 induces conformational change in Bcl-2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer cells.
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