GENERAL CATALOGUE
(R)-GSK-3685032
HY-139664A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-139664A
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medchemexpress.com/r-gsk-3685032.html
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Catalog No: HY-139664A
CAS No: 2170140-50-6
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
R -GSK-3685032 is the R-enantiomer of GSK-3685032. GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 ?M. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition.
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