GENERAL CATALOGUE
(R)-Afatinib
HY-10261E · 50 mg
MedChemExpress · Cat: HY-10261E
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medchemexpress.com/r-afatinib.html
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Catalog No: HY-10261E
CAS No: 439081-17-1
Category: JAK STAT Signaling
Pack Size: 50 mg
Brand: MedChemExpress
Description
R -Afatinib R -BIBW 2992 is the Afatinib isomer. Afatinib HY-10261 is an orally active, potent and irreversible dual specificity inhibitor of?ErbB?family EGFR?and?HER2 , with?IC50?values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for?EGFRwt, EGFRL858R,?EGFRL858R/T790M?and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma ESCC , non-small cell lung?cancer? NSCLC and gastric?cancer.
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