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PX-866, PI3-kinase inhibitor
ab142172 · 1 mg
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Catalog No: ab142172
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam
Description
MW 525.6 Da, Purity >98 %. Potent, irreversible PI3-kinase inhibitor. Inhibits purified phosphoinositide PtdIns -3-kinase IC50 = 0.1 nM and PtdIns-3-kinase signaling as assessed by phospho-Ser473-Akt levels in HT-29 colon cancer cells IC50 = 20 nM . Ring-opened analog of wortmannin ab120148 . Displays antitumor activity.
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