
ab285414 · 10 mg
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Description
MW 700.8 Da, Purity >98 %. Posaconazole is a broad-spectrum, second-generation triazole compound that displays antifungal activity. Posaconazole inhibits the growth of fungi by inhibiting the lanosterol 14alpha-demethylase enzyme IC50s range from 7-200 nM , which results in a disruption the synthesis of ergosterol, a key sterol necessary for fungal cell membrane integrity and for the function of certain membrane-bound proteins.






