Phospho-Histone H2A.X (Ser139) (2A9) Mouse Monoclonal Antibody

Description

EnkiLife offers the Phospho-Histone H2A.X (Ser139) (2A9) Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB,ICC/IF application. Alternative Names of Immunogen: H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,ICC/IF 1:50-1:200 Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Research Area: Epigenetics and Nuclear Signaling