BRAND STORE
PF-04449913 (Glasdegib)
ab287062 · 1 mg
AB
Verified Partner
Sign in to see pricing and request a quote.
Brand Store Product
No external links. Get your quote directly here.
Sponsored
Catalog No: ab287062
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam
Description
MW 374.4 Da, Purity >98 %. Potent and orally bioavailable smoothened SMO inhibitor. PF-04449913 binds to human SMO with an IC50 of 4 nM. It has been shown to attenuate leukemia stem cell self-renewal and cell cycle progression in primary acute myeloid leukemia cells and in an in vivo Drosophila model.
More from abcam
NYC-488, Calpain Inhibitor, calpain inhibitor
ab143563
Biochemicals
4-Hydrazino-7-nitrobenzofurazane hydrazine adduct
ab275359
Biochemicals
ABD-F, Fluorogenic reagent for thiol labeling
ab145273
Biochemicals
CNQX disodium salt (mM/ml), AMPA / kainate antagonist (water soluble)
ab144488
Biochemicals
Temocapril hydrochloride, ACE inhibitor
ab142951
Biochemicals
Fluvoxamine maleate, Serotonin reuptake inhibitor (SSRI)
ab141082
Biochemicals
Anisomycin, Protein synthesis inhibitor
ab120495
Biochemicals
PugNAc, hexosaminidase A and B inhibitor
ab144670
Biochemicals