

ab141117 · 10 mg
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Description
MW 523.7 Da, Purity >99 %. Potent, ATP-competitive fibroblast growth factor receptor 1 FGFR1 and FGFR3 inhibitor IC50 values are 21.5 and 5 nM respectively . Shows little activity at EGFR, InsR, MEK and cPKC. Effectively inhibits angiogenesis in vivo. Also impairs tumor growth and inhibits self-renewal of stem cells.






