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PD 168393, EGFR inhibitor
ab145187 · 1 mg
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Catalog No: ab145187
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam
Description
MW 369.2 Da, Purity >98 %. Potent, irreversible, cell-permeable, selective EGFR inhibitor IC50 values are 0.7, 0.08, 5.7, 12 and 15 nM for EGF receptor tyrosine kinase, erbB1, erbB2, erbB4 and SK-BR-3, respectively . Binds to the catalytic domain. Inhibits cancer cell growth. Blocks reactive astrogliosis and shows neuroprotective effects in vivo. .
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