
ab289849 · 1 mL
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Description
PD-0325901 ab289849 is a selective and ATP non-competitive MEK1/2 inhibitor that suppresses phosphorylation of ERK in murine colon 26 tumors IC50 = 0.33 nM . In combination with the GSK-3 inhibitor CHIR99021, prevents cell differentiation and sustains self-renewal of embryonic stem ES cells.






