GENERAL CATALOGUE
PARP14 inhibitor 2
HY-176456 · 50 mg
MedChemExpress · Cat: HY-176456
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medchemexpress.com/parp14-inhibitor-2.htmlCatalog No: HY-176456
CAS No: 3064731-00-3
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
PARP14 inhibitor 2 Compound 3 is an orally active and highly selective PARP14 inhibitor with an IC50 value of <30 nM. PARP14 inhibitor 2 inhibits the mono-ADP-ribosyltransferase activity of PARP14 and regulates IFN-? and IL-4 signaling, reversing protumor macrophage polarization and inhibiting anti-tumor inflammatory responses. PARP14 inhibitor 2 is promising for research of PARP14-related diseases such as tumors, atopic dermatitis and autoimmune diseases.