p57 Kip2 Rabbit Monoclonal Antibody

Description

EnkiLife offers the p57 Kip2 Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,IP application. Alternative Names of Immunogen: CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50 Background: p27 Kip1 is a member of the Cip/Kip family of cyclin-dependent kinase inhibitors. Like its relatives, p57 Kip2 and p21 Waf1/Cip1, the ability to enforce the G1 restriction point is derived from its inhibitory binding to CDK2/cyclin E and other CDK/cyclin complexes. Expression levels of p27 are upregulated in quiescent cells and in cells treated with cAMP or other negative cell cycle regulators. Research Area: Cell Biology