GENERAL CATALOGUE
OSU-53
HY-125535 · 50 mg
MedChemExpress · Cat: HY-125535
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Catalog No: HY-125535
CAS No: 1290069-19-0
Category: Autophagy
Pack Size: 50 mg
Brand: MedChemExpress
Description
OSU-53 is an orally active AMPK activator EC50: 0.3 ?M and a direct mTOR inhibitor. OSU-53 induces autophagy and increases conversion of LC3 I to LC3 II. OSU-53 also modulates energy homeostasis by suppressing fatty acid biosynthesis and shifting the metabolism to oxidation by up-regulating the expression of PGC1? and NRF-1. OSU-53 has antitumor activity in various tumor models, such as breast cancer and thyroid cancer.
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