

ab120467 · 5 mg
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Description
MW 392.5 Da. Cell-permeable dynamin I and dynamin II inhibitor IC50 values are 1.9 and 4.4 muM for inhibition of dynamin I and II GTPase, respectively . Targets the pleckstrin homology PH lipid binding domain. Competitive with phospholipid and non-competitive with GTP. Inhibits receptor-mediated endocytosis IC50 = 6.7 muM . Inhibits cancer cell growth.






