

ab144317 · 1 mg
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Description
MW 402.5 Da, Purity >98 %. Potent CDK1/cyclin B and CDK2/cyclin A3 inhibitor IC50 values are 9.5 and 5.4 nM for CDK1/cyclin B and CDK2/cyclin A3 respectively . Antiproliferative agent. Inhibits CDK4/D1, DYRK1A, PDK1 ROCKII IC50 values are 1.6, 0.9, 0.8 and 0.6 muM respectively . Induces G2/M cell cycle arrest. Shows antitumor effects in vivo..






