GENERAL CATALOGUE
NKL 22
HY-100384 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-100384
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medchemexpress.com/NKL-22.htmlCatalog No: HY-100384
CAS No: 537034-15-4
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
NKL 22 compound 4b is a potent and selective inhibitor of histone deacetylases HDAC , with an IC50 of 199 and 69 nM for HDAC1 and HDAC3, respectively. NKL 22 exhibits selectivity over HDAC2/4/5/7/8 IC50?1.59 ?M . NKL 22 ameliorates the disease phenotype and transcriptional abnormalities in Huntingtons disease transgenic mice.
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