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Niraparib hydrochloride
GENERAL CATALOGUE

Niraparib hydrochloride

HY-10619A · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-10619A

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Catalog No: HY-10619A
CAS No: 1038915-64-8
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

Niraparib hydrochloride MK-4827 hydrochloride is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

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