GENERAL CATALOGUE
Nemorubicin
HY-15794 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-15794
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Catalog No: HY-15794
CAS No: 108852-90-0
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Nemorubicin Methoxymorpholinyl doxorubicin is a Doxorubicin derivative with potent antitumor activity. Nemorubicin is highly cytotoxic to a variety of tumor cell lines presenting a multidrug-resistant phenotype. Nemorubicin not only intercalate into the duplex DNA, but also result in significant ligands for G-quadruplex DNA segments, stabilizing their structure. Nemorubicin requirs an intact nucleotide excision repair NER system to exert its activity.