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Nefazodone hydrochloride, 5-HT2A antagonist
ab120587 · 10 mg
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Catalog No: ab120587
Category: Biochemicals
Pack Size: 10 mg
Brand: abcam
Description
MW 506.5 Da, Purity >99 %. Potent 5-HT2A receptor antagonist Ki = 7.1 nM for inhibition of 3H ketanserin binding in rat cortex . Additionally blocks alpha1 adrenoceptors Ki values are 5.5 and 84 nM at alpha1 and alpha2, respectively . Acts as a serotonin-norepinephrine-dopamine reuptake inhibitor SNDRI Ki values are 220 and 555 nM at rat SERT and NET, respectively . Antidepressant.
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