GENERAL CATALOGUE
Navlimetostat
HY-139611 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-139611
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Catalog No: HY-139611
CAS No: 2630904-45-7
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Navlimetostat is a potent, orally active, selective PRMT5-MTA complex inhibitor, with IC50 of 3.6 and 20.5 nM for PRMT5-MTA and PRMT5. Navlimetostat binds to the PRMT5-MTA complex, with KD value of 0.14 pM. Navlimetostat shows antineoplastic activity in vitro and in vivo, and can be used for cancer study.
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