GENERAL CATALOGUE
Naratriptan hydrochloride
HY-B0197A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-B0197A
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Catalog No: HY-B0197A
CAS No: 143388-64-1
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Naratriptan GR-85548A hydrochloride is a selective 5-HT1B/1D receptor agonist. Naratriptan hydrochloride is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors EC50=0.11 ?M for dog basilar artery . Naratriptan hydrochloride also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan hydrochloride is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms.
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