GENERAL CATALOGUE
MS31
HY-125837 · 50 mg
MedChemExpress · Cat: HY-125837
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Catalog No: HY-125837
CAS No: 2366264-12-0
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
MS31 is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 SPIN1 inhibitor. MS31 potently inhibits the interactions between SPIN1 and H3K4me3 IC50=77 nM, AlphaLISA; 243 nM, FP . MS31 selectively binds Tudor domain II of SPIN1 Kd=91 nM . MS31 potently inhibits binding of trimethyllysine-containing peptides to SPIN1. MS31 is not toxic to nontumorigenic cells.