GENERAL CATALOGUE
Mosnodenvir
HY-153810 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-153810
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medchemexpress.com/mosnodenvir.htmlCatalog No: HY-153810
CAS No: 2890688-86-3
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Mosnodenvir JNJ-1802 is an orally active pan serotype dengue virus DENV inhibitor, with EC50 values ranging from 0.057 to 11 nM for four dengue virus DENV serotypes. Mosnodenvir blocks viral replication by inhibiting the formation of complexes between two viral proteins, nonstructural protein 3 NS3 and NS4B, thereby preventing the formation of new viral RNA. Mosnodenvir exhibits picomolar to nanomolar antiviral activity in vitro and has antiviral efficacy in mice and non-human primates.
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